What is the effect of co-morbid depression on the use of unscheduled hospital care by people with a long term condition?

Talk Code: 
Dr Caroline Anne Mitchell
om Ricketts, Emily Wood, John Soady, David Saxon, Joe Hulin, Sally Ohlsen
Author institutions: 
Sheffield School of Health and Related Research (ScHARR) & the Academic Unit of Primary Medical Care, University of Sheffield.


The primary healthcare system is reported to be less able to support people living with one or more long term conditions (LTC) where they are also experiencing a mental health problem. This may be evidenced by additional use of unscheduled hospital care by people with co-morbid mental and physical health problems. We wanted to quantify the size of this effect as part of a programme of research evaluating integrated care approaches that address both mental and physical health problems.


The study used a combined routine clinical database covering the whole of the adult population (age 18 and over) of Sheffield, a medium sized city in England (n=469,368). The bespoke dataset combined extracts from routine NHS records from primary and secondary care and linked at the person level. Cross-sectional data on all GP-recorded LTCs including depression as defined by QOF coding rule sets were included, together with longitudinal data on the use of scheduled and unscheduled hospital care. Analyses identified the extent of GP identified comorbidity between each LTC and depression, and the extent to which patients with LTCs and co-morbid depression used unscheduled care over a twelve month period in comparison to those with a LTC only. Logistic regression was used to determine the effects of depression after controlling for other potential confounding variables.


75,107 (16%) had a recorded diagnosis of depression. Of all patients with an identified LTC 20.9% also had a diagnosis of depression. Of all patients diagnosed with depression 50.9% had at least one LTC. The proportion of people who accessed unscheduled care increased as the number of LTCs increased. The proportion of individuals who had one or more 'unscheduled attendances' at hospital was 24% for those with a physical health LTC only, compared to 31.5% for those with a LTC and comorbid depression. This was a statistically significant association (p<.001). A logistic regression model was developed that controlled for a number of confounding factors. Those patients with depression were 1.59 times more likely to make use of unscheduled care over the twelve month period, after controlling for other variables.


In this current study, for people living with a LTC, the addition of depression increases use of unscheduled care such as emergency department attendance. Primary care approaches that integrate self-management of LTCs and depression may be particularly useful given the extent and impact of this comorbidity.

Submitted by: 
Caroline Mitchell
Funding acknowledgement: 
NIHR CLAHRC Yorkshire and Humber grant number IS-CLA-0113-10020 This report presents independent research by the National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care Yorkshire and Humber (NIHR CLAHRC YH). www.clahrc-yh.nir.ac.uk. The views and opinions expressed are those of the authors, and not necessarily those of the NHS, the NIHR or the Department of Health.